USDA Actions to Prevent Bovine Spongiform Encephalopathy (BSE) 1988 Establishes BSE Working Group to regularly review the available science and suggest appropriate regulatory measures. 1989 Bans the importation of all ruminants, bovine semen, embryos, and meat and bone meal from the United Kingdom (U.K.), where BSE has been officially diagnosed. 1990 Begins BSE educational outreach, educating veterinary practitioners, veterinary laboratory diagnosticians, industry, and producers about the clinical signs and pathology of BSE. Initiates an active BSE surveillance program, including histopathological examination of brain tissue of high-risk cattle. Initiates traceback of cattle imported from the U.K. 1991 Conducts BSE risk analysis. Enacts formal regulations to prohibit the importation of most ruminant products from any country known to have BSE. 1993 Expands BSE surveillance program to include examination of brain tissue from "downer" cows. Updates the 1991 BSE risk analysis. 1994 Expands diagnostic testing to include supplemental tests for abnormal prion proteins, which are indicative of BSE. 1996 Updates the 1993 BSE risk analysis. 1997 Prohibits importation of live ruminants and most ruminant products from Europe. Supports FDA regulation prohibiting the use of most mammalian protein in the manufacture of animal feeds given to ruminants. 1998 Enters into cooperative agreement with Harvard University to analyze and evaluate the Department's BSE prevention measures. #