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Guidance Documents

Welcome to the USDA Guidance Portal. This web portal is a searchable, indexed database that contains guidance documents issued by USDA and its agencies that are in effect today. The guidance documents contained herein lack the force and effect of law, unless expressly authorized by statute or incorporated into a contract. The USDA may not cite, use, or rely on any guidance that is not available through this guidance portal, except to establish historical facts. The Department reserves the right to remove any such documents at any time from this Portal.

USDA is continually updating its portal and agency websites to ensure that current guidance is on the portal and obsolete guidance is removed.

If you have feedback or problems accessing a guidance document, please contact USDAGuidance@usda.gov.

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Subject Issuing Agency Topic Latest Date Issued
Am I Regulated? (AIR) Process Guide for Submission of AIR Inquiries Biotechnology, Am I Regulated January 6, 2026
Permit User Guide with Reference To 7 CFR Part 340 – Introduction of Organisms and Products Altered or Produced Through Genetic Engineering Which are Plant Pests or Which There is Reason to Believe are Plant Pests Biotechnology, Permits June 12, 2025
APHIS eFile Job Aid, APHIS 2000 Authorization Application and Compliance Reporting Biotechnology, Applications, Reporting, Job Aid June 12, 2025
Petition User Guide with Reference To 7 CFR Part 340 –Introduction of Organisms and Products Altered or Produced Through Genetic Engineering Which are Plant Pests or Which There is Reason to Believe are Plant Pests Biotechnology, Petitions February 19, 2025
Guide for Submitting Confidential Business Information (CBI) in Submission to APHIS BRS Biotechnology February 7, 2025
Guide for Submitting Permit Applications for Microorganisms Developed Using Genetic Engineering Under 7CFR Part 340 Biotechnology, Permitting September 10, 2024
Standing Operation Procedure (SOP) Template for APHIS BRS Plant Permits Biotechnology, Permitting September 14, 2023
Petunia spp. Biotechnology, Flower imports January 19, 2021
General Document Preparation Guidelines For Submission to BRS Biotechnology, Document Guidelines September 5, 2018
Minimum Separation Distances to be used for Confined Field Tests of Certain Genetically Engineered Plants Biotechnology, Permitting August 1, 2013