As the new decade unfolds, a remarkable trend is evident in the world. In 2020, the global community and the media have been focused on the surge of a novel virus, the spread of African swine fever, wildfires, outbreak of desert locust, and debates on the safe use of agricultural technology. These challenges have similar characteristics – they span borders, have significant economic outcomes, and require global scientific collaboration to effectively address them. Public policy makers look to researchers to advance critical knowledge and offer solutions, and this research requires international collaboration. For success, however, efforts must be grounded in foundational principles and values that support international science.